Epithelial TRPV1 Signaling Accelerates Gingival Epithelial Cell Proliferation

The role of nickel accumulation and epithelial cell proliferation in orthodontic treatment-induced gingival overgrowth.

The aim of this study was to investigate the role of nickel in orthodontic treatment-induced gingival hyperplasia. The nickel concentration in gingival tissues with and without overgrowth, histopathology of gingival overgrowth, and epithelial cell proliferation response to different nickel concentrations were analysed. Ten patients receiving orthodontic therapy (eight females and two males, mea...

Interleukin-6 production and epithelial cell signaling by telomerase immortalized gingival keratinocytes in Porphyromonas gingivalis infection

Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade.

The surface of the airway epithelium represents a battleground in which the host intercepts signals from pathogens and activates epithelial defenses to combat infection. Wound repair is an essential function of the airway epithelium in response to injury in chronic airway diseases, and inhaled pathogens such as Pseudomonas bacteria are implicated in the pathobiology of several of these diseases...

Irsogladine maleate regulates gingival epithelial barrier function and intercellular communication in gingival epithelial cells

Epithelial cells function as a mechanical barrier against invasion by pathogenic organisms and promote intercellular communication through cell-cell junction complexes. Therefore, the permeability and homeostasis of the gingival epithelial cell layer indicates a defensive capability against invasion by periodontal pathogens. Irsogladine maleate is a medication for gastric ulcer, and is also kno...

Changing pattern of epithelial cell abnormalities using revised Bethesda system

Objective(s): In developing countries and worldwide cervical cancer is an important cause of   female mortality. Reports describing the frequency and pattern of abnormal Pap smears in Saudi Arabia, using the revised Bethesda system (RBS) are very few. The current study was conducted to explore the changing pattern of epithelial cell abnormalities (ECA) detected in Pap smears (PS) in females of ...